Repeatability of QuantiFERON-TB Gold In-Tube Assay Results Near Cut-Off Points
نویسندگان
چکیده
منابع مشابه
Repeatability of QuantiFERON-TB Gold In-Tube Assay Results Near Cut-Off Points
Dear Editor, Interferon (IFN)-γ release assay (IGRA) is a functional assay used to measure T cell responses to Mycobacterium tuberculosis-specific antigens in whole blood or blood-derived mononuclear cells [1, 2]. The QuantiFERON-TB Gold In-Tube (QFT-GIT; Cellestis, Carnegie, Australia) is a commercially available IGRA. Significant within-subject variability in QFT-GIT results has been reported...
متن کاملInvestigation of false-positive results given by the QuantiFERON-TB Gold In-Tube assay.
We investigated a sudden increase in the rate of positive QuantiFERON-TB Gold In-Tube results from 10% to 31% at a U.S. academic institution. Direct comparison of the TB antigen tubes with tubes from a different lot number identified that a potential problem with the TB antigen vials in a certain tube lot was the likely cause of the elevated positive rate. The underlying defect remains unknown....
متن کاملInvestigation of false-positive results by the QuantiFERON-TB Gold In-Tube assay
1 Madeline Slater, Julie Parsonnet, Niaz Banaei 2 3 Division of Infectious Diseases and Geographic Medicine, Department of Medicine and 4 Pathology, Stanford University School of Medicine, Palo Alto, California; Clinical 5 Microbiology Laboratory, Stanford University Medical Center, Palo Alto, California 6 7 Running Title: False-positive QuantiFERON-TB Gold In-Tube results 8 9 Corresponding aut...
متن کاملImmediate incubation reduces indeterminate results for QuantiFERON-TB Gold in-tube assay.
In vitro gamma interferon release assays (IGRAs) are increasingly used as an alternative to the traditional tuberculin skin test for the diagnosis of latent Mycobacterium tuberculosis infection. Evaluation of the QuantiFERON-TB Gold in-tube assay (QFT-IT) prior to large-scale implementation at the Stanford Hospital and Clinics for a health care worker screening program revealed a critical prean...
متن کاملUnusual Interferon Gamma Measurements with QuantiFERON-TB Gold and QuantiFERON-TB Gold In-Tube Tests
INTRODUCTION Interferon gamma (IFN-γ) release assays, such as QuantiFERON®-TB Gold test (QFT-G) and QuantiFERON®-TB Gold In-Tube test (QFT-GIT) are designed to detect M. tuberculosis (Mtb) infection. Recognition of unusual IFN-γ measurements may help indicate inaccurate results. METHODS We examined QFT-G and QFT-GIT results from subjects who had two or more tests completed. We classified unus...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annals of Laboratory Medicine
سال: 2016
ISSN: 2234-3806,2234-3814
DOI: 10.3343/alm.2016.36.1.76